If the security of your portable data is a concern for you, then MyIDKey might be just the solution you're looking for. This little USB drive offers a biometric scanner which unlocks the drive when it senses the proper thumbprint.
While the 2GB of storage might seem small, not all of your portable data needs to be secured. This is an ideal size for password files, scripts, business documents, etc. Luckily, if you do need more storage, there is also a 16GB version available.
The 2GB will be available Q2 for $99 and the 16GB will be available for $199.